Optics-Integrated Microfluidic Platforms for Biomolecular Analyses
نویسندگان
چکیده
منابع مشابه
Integrated Micro-Optics for Microfluidic Systems
Microfluidic systems have a large variety of applications in biomedicine and life sciences. One of the problems occurring in practical systems is the adhesion of cells and micro-particles to the walls of microfluidic channels and reservoirs. For scientific examinations, e.g. for drug testing, it is necessary to expose specific test cells to different media. The cells are moved between the reser...
متن کاملAn integrated optics microfluidic device for detecting single DNA molecules.
A fluorescence-based integrated optics microfluidic device is presented, capable of detecting single DNA molecules in a high throughput and reproducible manner. The device integrates microfluidics for DNA stretching with two optical elements for single molecule detection (SMD): a plano-aspheric refractive lens for fluorescence excitation (illuminator) and a solid parabolic reflective mirror for...
متن کاملMicrofluidic platforms for mechanobiology.
Mechanotransduction has been a topic of considerable interest since early studies demonstrated a link between mechanical force and biological response. Until recently, studies of fundamental phenomena were based either on in vivo experiments with limited control or direct access, or on large-scale in vitro studies lacking many of the potentially important physiological factors. With the advent ...
متن کاملPerformance Comparison of Two LabChip Microfluidic Platforms for Protein, DNA, and RNA Analyses
Introduction The analysis of any mixture, including complex biological material, includes its separation into single components and an assessment of their quantities in the sample. For biological samples, measurements of nucleic acids (both DNA and RNA) and proteins are the predominant assays. However, the sample complexity in these materials necessitates the combination of a highly sensitive d...
متن کاملA Rapid Micromixer for Centrifugal Microfluidic Platforms
This paper presents an innovative mixing technology for centrifugal microfluidic platforms actuated using a specially designed flyball governor. The multilayer microfluidic disc was fabricated using a polydimethylsiloxane (PDMS) replica molding process with a soft lithography technique. The operational principle is based on the interaction between the elastic covering membrane and an actuator p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2016
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2016.03.018